One of the most effective drugs for erectile dysfunction is Phentolamine, which has a wide range of positive characteristics. More than 50% of the patients taking this drug note a significant improvement. But if you exceed the dosage of 40 mg, it can cause adverse effects.
Despite the successful clinical studies, Apomorphine was removed from the licensed development. The main reason was the side effects in the form of severe nausea attacks.
Sildenafil (Viagra) is the licensed medicine, whose pharmacological action is aimed at the elimination of erectile dysfunction of any origin. The principle of its action is reflected in preserving cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of cavernous bodies, destroyed by PDE-5 inhibitors, which, in its turn, blocks this drug. Under the action of Viagra the blood vessels relax and improve the blood flow to the penis, which provides long erection.
The use of Viagra has positive responses in more than 80% of cases of minor erectile dysfunctions, more than 60 % (in case of vascular genesis), and more than 50 % (if you have diabetes of 1 or 2 type).
The main purpose of Sildenafil is a recovery of erection, and not an increase of visual effect. The use of drug is not recommended even in case of minimum disruptions.
As any other medicine, Sildenafil (Viagra) has some adverse effects.
– Blood rush to the face.
– Digestive problems.
– Reduced tone of lower esophageal sphincter.
– Color vision deficiency.
Antidepressants are often prescribed to the depressed patients with erectile dysfunction.